[D-Pro2,D-Phe7,D-Trp9]-Substance P ( ——— )

产品货号. M41635 CAS No. 77275-70-8

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Datasheet

HNMR

HPLC

MSDS

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产品名称

[D-Pro2,D-Phe7,D-Trp9]-Substance P
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

[D-Pro2,D-Phe7,D-Trp9] Substance P 是 Substance P 的类似物。[D-Pro2,D-Phe7,D-Trp9] Substance P 是 Substance P 的抑制剂。[D-Pro2,D-Phe7,D-Trp9] Substance P 间接收缩豚鼠回肠。
产品描述

[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly.
体外实验

[D-Pro2,D-Phe7,D-Trp9] Substance P (1-2 mg/kg; i.v.; once) inhibits the salivary secretion which was induced by Substance P in rats. In the dosage range at 1-1.5 mg/kg slightly increases the blood pressure.
体内实验

[D-Pro2,D-Phe7,D-Trp9] Substance P (10-100 μM; 2 min or 10 min) produces dose-related contractions of the guinea-pig ileum and in the rabbit external jugular vein.
同义词

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通路

Others
靶点

Other Targets
受体

Substance P
研究领域

———
适应症

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1. Hawcock AB, et al. Agonist effects of D-Pro2,D-Phe7,D-Trp9substance P--evidence for different receptors. Eur J Pharmacol. 1982 May 7;80(1):135-8.?

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